Organic Chemistry

1. Define and use the terms of organic chemistry.
2. Define and designate the different classes of organic compounds and reproduce their structures
3. Explain the chemical transformations and mechanisms for alkanes, alkenes, alkynes, alkyl halides, alcohols, aromatic compounds, carbonyl and carboxylic compounds
4. Analyze and apply the principles of reaction mechanisms of all types of organic compounds with functional groups
5. Apply the stereochemical considerations in transformations of organic molecules
6. Prepare, isolate, purify and identify some representatives of organic compounds related to the fundamental knowledge of organic chemistry
7. Use the knowledge and skills of organic chemistry for applied in resolving of millitary engineering problems

ex cathedra

ex cathedra

using system for e-learning (Merlin)

individual

1. Lectures: Carbon compounds and chemical bonds: octete rule, Lewis structures, formal charge, resonance Seminar: Additional problems on bond and isomerism: bonding and Lewis structures, structural isomers, structural formulas. Exercises: Application of thin layer chromatography (TLC) for identification of organic compounds.
2. Lectures: Classes of carbon compounds: functional groups, hydrocarbons: reperesentative alkanes, alkenes, alkynes and aromatic compounds Seminar: Additional problems on bond and isomerism: formal charge, resonance, electronic structure and molecular geometry, classification of organic compounds Exercises: Application of thin layer chromatography (TLC) for purification of organic compounds.
3. Lectures: Alkanes and cycloalkanes: nomenclature, conformational analysis, introduction to synthesis Seminar: Additional problems on alkanes and cycloalkanes: nomenclature and structural formulas, conformations, cis-trans isomerism, reactions of alkanes: combustion and halogenation Exercises: Application of column chromatography (CC) for identification of organic compounds.
4. Lectures: Stereochemistry: chiral molecules, constitutional isomers, stereoisomers, enantiomers, optical activity Seminar: Additional problems on stereochemistry: definitions and stereogenic centers, stereoisomers, the R-S and E-Z conventions, Fischer and Newman projections, chemical reactions. Exercises: Application of column chromatography (CC) for purification of organic compounds.
5. Lectures: Nucleophilic substitution (SN1 i SN2) and elimination reactions of alkyl halides, kinetics Seminar: Additional problems on organic halogen compounds: alkyle halide structure, nucleophilic substitution reactions of alkyl halides, Exercises: Purification of organic compounds by using recrystalization from water as solvent.
6. Lectures: Stereochemistry and mechanism for SN1 and SN2 reactions, substitution versus elimination Seminar: Additional problems on stereochemistry of nucleophilic substitution reactions of alkyl halides Exercises: Purification of organic compounds by using recrystalization from ethanol as solvent.
7. Lectures: Alkenes and alkynes: properties and synthesis, elimination and addition reactions Seminar: Additional problems on alkenes and alkynes: nomenclature and structure, electrophilic addition to alkenes, reactions of conjugated dienes, other reaction Exercises: Synthesis of alkyl halides by nucleophilic substitution recation: Synthesis of n-butyl bromide
8. Lectures: Alcohols and ethers: structure and nomenclature, synthesis and reactions Seminar: Additional problems on alcohols, ethers and epoxides: structure, nomenclature and properties, preparation and reaction of Grignard reagents, preparation and behavior of ethers in acids and bases, preparations and reactions of epoxides, cyclic ethers. Exercises: Synthesis of alkyl halides by nucleophilic substitution recation: Synthesis of n-butyl bromide
9. Lectures: Aromatic compounds: the Kekulé structure of benzene, aromaticity, nomenclature of benzene derivatives, Seminar: Additional problems on aromatic compounds: nomenclature and structural formulas, aromaticity and resonance Exercises: Synthesis of alkyl halides by nucleophilic substitution recation: Synthesis of n-butyl bromide
10. Lectures: Aromatic compounds: reactions of benzene, electrophylic aromatic subtitutions Seminar: Mechanism of electrophilic aromatic substitution and reactions of substituted benzenes: activating and directing effects Exercises: Synthesis of alkyl halides by nucleophilic substitution recation: Synthesis of n-butyl bromide
11. Lectures: Aldehyde and ketones: nomenclature, synthesis, nucleophilic addition to the carbonyl group, aldol reaction Seminar: Additional problems on aldehydes and ketones: synthesis and reactions, reactions with Grignard reagents, oxidations and reductions, enols, enolates, the aldol reaction. Exercises: Synthesis of alkyl halides by nucleophilic substitution recation: Synthesis of n-butyl bromide
12. Lectures: Carboxylic acids and their derivatives: nomenclature, nucleophilic addition-elimination reaction at the acyl carbon Seminar: Additional problems on carboxylic acids and their derivatives: nomenclature and structure, synthesis, nomenclature and structure of carboxylic acid derivatives, synthesis and reactions of esters, the Claisen condensation Exercises: Synthesis of carboxylic acid derivatives by nucleophilic substitution reactions: Synthesis of ethyl acetate by esterification of acetic acid with ethanol
13. Lectures: Carboxylic acids and their derivatives: nomenclature, nucleophilic addition-elimination reaction at the acyl carbon Seminar: Additional problems on carboxylic acids and their derivatives: nomenclature and structure, synthesis, nomenclature and structure of carboxylic acid derivatives, synthesis and reactions of esters, the Claisen condensation Exercises: Synthesis of carboxylic acid derivatives by nucleophilic substitution reactions: Synthesis of ethyl acetate by esterification of acetic acid with ethanol
14. Lectures: Amines: nomenclature and structure of amines, basicity of amines, synthesis of amines. Seminar: Additional problems on amines and related nitrogen compounds: nomenclature and structure of amines, properties of amines and quaternary ammonium salts, preparation and reactions of amines Exercises: Synthesis of carboxylic acid derivatives by nucleophilic substitution reactions: Synthesis of ethyl acetate by esterification of acetic acid with ethanol
15. Lectures: Introduction to spectroscopic methods in determination of organic compounds: Nuclear magnetic resonance (NMR) and mass spectrometry (MS) Seminar: Examples related to spectroscopy and structure determinations by 1H and 13C NMR spectroscopy and mass spectrometry. Exercises: Synthesis of carboxylic acid derivatives by nucleophilic substitution reactions: Synthesis of ethyl acetate by esterification of acetic acid with ethanol