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Applied Organic Chemistry

Applied Organic Chemistry

Data is displayed for the academic year: 2025./2026.

Course Description

Explain the relationship between chemical structure, physical and chemical properties of organic compounds and reaction mechanisms. Learn to apply spectroscopic methods (NMR and MS) to determine the structure of organic molecules. Perform multistep synthesis of selected classes of macromolecules and structural characterization by spectroscopic methods.

Study Programmes

undergraduate
Chemical, Biological, Radiological and Nuclear Defence - course
(7. semester)

Learning Outcomes

  1. Recognize, differentiate, classify and present the structure of organic compounds
  2. Connect the chemical structure of the physical and chemical properties of organic compounds
  3. Analyze and connect the reaction mechanisms with the properties and structure of selected classes of organic compounds
  4. Apply the reaction mechanism of the functional group transformations in the macromolecules structures
  5. Prepare, isolate, purify and identify selected organic macromolecules
  6. Summarize, analyze and interpret the results, and conclude on the type of organic molecule evaluation of physicochemical and spectroscopic results

Forms of Teaching

Lectures

ex cathedra

Partial e-learning

using system for e-learning (Merlin)

Laboratory

individual

Week by Week Schedule

  1. Lectures: Classification and reactions of hydrocarbons (alkanes, alkenes, cycloalkanes) and aromatic compounds Seminar: Synthesis of 2,4-dimethoxypyrimidine from pyrimidine and phosphorus oxychloride by multistep synthesis
  2. Lectures: Classification and reactions of halogenated hydrocarbons Seminar: Isolation of 2,4-dichloropyrimidine
  3. Lectures: Organic compounds with oxygen and nitrogen Seminar: Purification of 2,4-dichloropyrimidine
  4. Lectures: Organometallic organic compounds: organomercury, organophosphorus and organopalladium compounds Seminar: Identification of 2,4-dichloropyrimidine
  5. Lectures: Polymers and polymerization reactions Seminar: Synthesis of 2,4-dimethoxypyrimidine
  6. Lectures: Carbohydrates: monosaccharides, disaccharides and polysaccharides Seminar: Isolation of 2,4-dimethoxypyrimidine
  7. Lectures: Nucleic acids and proteins Seminar: Purification of 2,4-dimethoxypyrimidine
  8. Lectures: Biologically important natural and synthetic derivatives of carbohydrates and nucleic acids Seminar: Identification of the isolated compounds by 1H and 13C NMR spectroscopy and MS spectrometry
  9. Lectures: Oils and fats: drying oils, phospholipids and soaps Seminar: Synthesis of pentaacethyl-D-glucose
  10. Lectures: Animal, vegetable and mineral waxes, natural terpene resins and varnishes Seminar: Isolation of pentaacethyl-D-glucose
  11. Lectures: Coloring and dyes: natural and synthetic dyes Seminar: Purification of pentaacethyl-D-glucose
  12. Lectures: Application of 1H NMR spectroscopy in the determination of organic compounds structure Seminar: Structural charactzerization of pentaacethyl-D-glucose
  13. Lectures: Application of 1H NMR spectroscopy in the determination of organic compounds structure Seminar: Synthesis of biodiesel by transesterification reaction
  14. Lectures: Application of 13C NMR spectroscopy in the determination of organic compounds structure Seminar: Isolation and purification of biodisel
  15. Lectures: Application of MS spectrometry in the determination of organic compounds structure Seminar: Identification of biodisel by MS spectrometry

Literature

R. Bruckner (2002.), Advanced organic chemistry, Elsevier
R. M. Silverstein, F. X. Webster, D. J. Kiemle (2005.), Spectroscopic identification of organic compounds, John Willey Sons, 2005., John Wiley&Sons

For students

General

ID 282241
  Winter semester
3.0 ECTS
L0 English Level
L3 e-Learning
30 Lectures
15 Laboratory exercises